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Ayoub Qanir (M, 37)
Immortal since Oct 10, 2009
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    Paper-based Microfluidic Devices

    Harvard ENSC E-155
    Professor Fawwaz Habbal & professor Anas Chalah
    Student: Ayoub Qanir

    March 19th, 2012 | Rapid prototyping of paper-based microfluidics with wax for low cost

    (1) Main Goal of the paper
    How to fabricate paper-based microfluidic devices for low cost usage, high portability and mobility?
    The authors share with us a gripping break down and a meticulous walk-through the process of fabricating paper-based microdevices. The paper also shares important variables, such as waxing versus patterning with SU-8 or PDMS, making the paper-based devices more attractive in limited-resources regions.

    (2) The Application
    - The paper discusses Whitesides’ paper microfluidic diagnostic platform with the capability to perform multiplexed assays and realize inexpensive on-site analysis.

    (3) Strong and Weak Points
    Strong Points
    - the paper brings up a previous paper-based example that would still be much less cost-effective compared to the one discussed in the paper—with the main difference being patterning with wax versus patterning with SU-8 or PDMS.
    - The paper does a great job walking a non-professional fabricator through the step by step process to building paper-based devices.
    - The many alternatives to fabricating the paper-based devices is clearly dissected.
    - The paper specifically targets non-professional users in limited-resources regions which seems to be the main goal of fabricating low-cost paper-based devices.
    -The paper phenomenally breaks down the three main variables making paper-based devices more attractive; The production process, production speed, cost effectiveness and environment awareness.

    Weak points
    - The paper vaguely discusses actual testing ground where paper-based microfluidic devices made a difference.

    (4) My Suggestion
    - I understand the paper-based devices are a novel manner of fabrication, though it would have given the process even more credibility and confidence of usability if the authors were able to bring up a real life contamination event or testing ground where the testers chose to fabricate paper-based device instead of testing with a more conventional microfluidic devices.

    (5) Possible Future Applications
    - The further development and dissemination of paper-based microfluidic devices in developing countries with high risk of malignant propagation could truly revolutionize the concept of medecine and allow for faster, more efficient defense response to any kind of disease. We could be designing paper-based devices in the developed countries sharing the design via web with any developing region, ground-zero of any contamination, where tests could be performed by non-proficient users in remote areas..

    (6) My Final Decision
    Great paper with stunning break-down with a smooth information processing.
    Grant: Approved


    Fri, Apr 27, 2012  Permanent link

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