Member 1648
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Self Evolving Minds & Machines
The Social Brain
The truth knocks on the door and you say, "Go away, I'm looking for the truth," and so it goes away. (Robert Pirsig)
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    "Computer Game's High Score Could Earn The Nobel Prize In Medicine"

    "A new game, named Foldit, turns protein folding into a competitive sport. Introductory levels teach the rules, which are the same laws of physics by which protein strands curl and twist into three-dimensional shapes — key for biological mysteries ranging from Alzheimer's to vaccines.

    After about 20 minutes of training, people feel like they're playing a video game but are actually mouse-clicking in the name of medical science. The free program is at

    'We're hopefully going to change the way science is done, and who it's done by,' said Popovic, who presented the project today at the Games for Health meeting in Baltimore. 'Our ultimate goal is to have ordinary people play the game and eventually be candidates for winning the Nobel Prize.'

    Proteins, of which there are more than 100,000 different kinds in the human body, form every cell, make up the immune system and set the speed of chemical reactions. We know many proteins' genetic sequence, but don't know how they fold up into complex shapes whose nooks and crannies play crucial biological roles.

    Computer simulators calculate all possible protein shapes, but this is a mathematical problem so huge that all the computers in the world would take centuries to solve it. In 2005, Baker developed a project named Rosetta@home that taps into volunteers' computer time all around the world. But even 200,000 volunteers aren't enough.

    'Long-term, I'm hoping that we can get a significant fraction of the world's population engaged in solving critical problems in world health, and doing it collaboratively and successfully through the game,' David Baker, a UW professor of biochemistry and Howard Hughes Medical Institute investigator, said. 'We're trying to use the brain power of people all around the world to advance biomedical research.'

    Foldit includes elements of multiplayer games in which people can team up, chat with other players and create online profiles. Over time the researchers will analyze people's moves to see how the top players solve puzzles. This information will be fed back into the game's design so the game's tools and format can evolve."

    See the original article here.
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    I think what I appreciate most about this revolutionary project is that it is a microcosm of the potentially unfathomable power a humanity connected and singularly-focused can harness.

    It brings to mind the Pangea Day event which occurred this past Saturday, where 24 short films made by anyone and everyone around the world were watched on “millions of screens and shared at more than 1,000 events and parties.” The concept was to fuse the differentiating consciousnesses of as many individuals as possible into a collective human experience through personal and potent films to promote world peace.

    It seems to me both of these projects are original and substantive attempts at employing modern tools to amalgamate the masses on a level never before reached to thrust the progress of the species forward. It'll be interesting to track the concentric circling of Foldit and Pangea Day and see what fruit they do or do not bear. For I think either way, there is a lot to be learned from their successes as well as their failures.

    I'd also be curious to know what potential the Collective thinks such endeavors really have, what parallel projects I may have missed, and any ideas one may have for new projects dedicated to funneling vast pools of brainpower into solving a weighty human problem?

    You can see the Pangea Day films here.

    Tue, May 13, 2008  Permanent link

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    Spaceweaver     Tue, May 13, 2008  Permanent link
    Am playing with Foldit, an interesting challenge !
         Tue, May 13, 2008  Permanent link
    This game looks like something that I won't feel like I'm wasting my time while playing, so I'll get it working on my computer when I can find the time... it looks really awesome :)